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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SP1 All Species: 13.64
Human Site: T579 Identified Species: 33.33
UniProt: P08047 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.22
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P08047 NP_003100.1 785 80693 T579 G D G I H D D T A G G E E G E
Chimpanzee Pan troglodytes Q19A40 323 33082 L129 V Q T P C S E L A P A S G A A
Rhesus Macaque Macaca mulatta XP_001104948 786 80693 T580 G D G I H D D T A G G E E G E
Dog Lupus familis XP_543633 778 79965 T572 G D G I H D D T A G G E E G E
Cat Felis silvestris
Mouse Mus musculus O89090 784 80713 E580 G G D G I H D E T A G G E G E
Rat Rattus norvegicus Q01714 786 80753 T580 G D G I H D E T A G G E E G E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514802 816 85651 H610 L N T N D L T H L R V Q V V D
Chicken Gallus gallus Q90WR8 771 80932 H565 L N T N D L T H L R V Q V V D
Frog Xenopus laevis NP_001084888 723 76386 E523 H S A M E E G E T S P D P Q P
Zebra Danio Brachydanio rerio NP_956418 714 74632 V520 S A P V T V T V G N I S N A V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 21.9 99.3 96.9 N.A. 95.5 96.3 N.A. 34.9 36.5 68.4 36.5 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 27.5 99.7 97.3 N.A. 97 97.7 N.A. 51.3 53.1 77.3 51.8 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 6.6 100 100 N.A. 40 93.3 N.A. 0 0 0 0 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 13.3 100 100 N.A. 40 100 N.A. 20 20 20 6.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 10 0 0 0 0 0 50 10 10 0 0 20 10 % A
% Cys: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 40 10 0 20 40 40 0 0 0 0 10 0 0 20 % D
% Glu: 0 0 0 0 10 10 20 20 0 0 0 40 50 0 50 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 50 10 40 10 0 0 10 0 10 40 50 10 10 50 0 % G
% His: 10 0 0 0 40 10 0 20 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 40 10 0 0 0 0 0 10 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 20 0 0 0 0 20 0 10 20 0 0 0 0 0 0 % L
% Met: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 20 0 20 0 0 0 0 0 10 0 0 10 0 0 % N
% Pro: 0 0 10 10 0 0 0 0 0 10 10 0 10 0 10 % P
% Gln: 0 10 0 0 0 0 0 0 0 0 0 20 0 10 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 20 0 0 0 0 0 % R
% Ser: 10 10 0 0 0 10 0 0 0 10 0 20 0 0 0 % S
% Thr: 0 0 30 0 10 0 30 40 20 0 0 0 0 0 0 % T
% Val: 10 0 0 10 0 10 0 10 0 0 20 0 20 20 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _